When setting up an existing .NET application on a fresh machine you may see the following error:
"Could not load file or assembly 'Some.Assembly.Name' or one of its dependencies. Access is denied."
A potential quick solution is to go to “C:\WINDOWS\Microsoft.NET\Framework\v2.0.50727\Temporary ASP.NET Files” and modify the security settings for the folder to grant "Full control" to the 'users' group.
Not ideal but it will get the development environment up-and-running.